MDMB-FUBICA

MDMB-FUBICA
Legal status
Legal status	CA: Schedule II; DE: NpSG (Industrial and scientific use only); UK: Class B; Illegal in Sweden;
Identifiers
	IUPAC name methyl (2S)-2-({1-[(4-fluorophenyl)methyl]-1H-indol-3-yl}formamido)-3,3-dimethylbutanoate;
CAS Number	1971007-91-6 ;
PubChem CID	129522107;
ChemSpider	57621561;
UNII	K53ZMB4NR6;
Chemical and physical data
Formula	C23H25FN2O3
Molar mass	396.462 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES COC(=O)[C@@H](NC(=O)c1cn(Cc2ccc(F)cc2)c3ccccc13)C(C)(C)C;
	InChI InChI=1S/C23H25FN2O3/c1-23(2,3)20(22(28)29-4)25-21(27)18-14-26(19-8-6-5-7-17(18)19)13-15-9-11-16(24)12-10-15/h5-12,14,20H,13H2,1-4H3,(H,25,27)/t20-/m1/s1; Key:RVAWIZIGOSKPBP-HXUWFJFHSA-N;

MDMB-FUBICA is an indole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB₁ receptor and has been sold online as a designer drug.^[1]

It was first detected by the EMCDDA in Sweden in February 2015.^[2] It is often sold in e-liquid form for use in an electronic cigarette.^[3]

Side effects

MDMB-FUBICA's indazole analogue MDMB-FUBINACA has been linked to at least 1000 hospitalisations and 40 deaths as a consequence of intoxication as of March 2015.^[4]

Legality

MDMB-FUBICA is banned in Sweden.^[5]

References

^ Wagmann L, Stiller RG, Fischmann S, Westphal F, Meyer MR (October 2022). "Going deeper into the toxicokinetics of synthetic cannabinoids: in vitro contribution of human carboxylesterases". Archives of Toxicology. 96 (10): 2755–2766. doi:10.1007/s00204-022-03332-z. PMC 9352624. PMID 35788413.
^ "Hamarosan: 2015. Évi Európai Kábítószer - Jelentés" [Coming soon: 2015. Annual European Drugs - Report] (PDF). Hungarian National Focal Point (NFP). June 2015. Retrieved 23 July 2015.
^ Peace MR, Krakowiak RI, Wolf CE, Poklis A, Poklis JL (February 2017). "Identification of MDMB-FUBINACA in commercially available e-liquid formulations sold for use in electronic cigarettes". Forensic Science International. 271: 92–97. doi:10.1016/j.forsciint.2016.12.031. PMC 5511053. PMID 28076838.
^ "Очередная жертва спайса" [Another victim of spice]. Federal Drug Control Service of the Russian Federation. 17 March 2015. Archived from the original on 14 July 2015. Retrieved 24 July 2015.
^ "23 nya ämnen kan klassas som narkotika eller hälsofarlig vara" [23 new substances can be classified as narcotics or health hazards]. Folkhälsomyndigheten (The Public Health Authority). 1 June 2015. Retrieved 24 July 2015.

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[1] Wagmann L, Stiller RG, Fischmann S, Westphal F, Meyer MR (October 2022). "Going deeper into the toxicokinetics of synthetic cannabinoids: in vitro contribution of human carboxylesterases". Archives of Toxicology. 96 (10): 2755–2766. doi:10.1007/s00204-022-03332-z. PMC 9352624. PMID 35788413.

[2] "Hamarosan: 2015. Évi Európai Kábítószer - Jelentés" [Coming soon: 2015. Annual European Drugs - Report] (PDF). Hungarian National Focal Point (NFP). June 2015. Retrieved 23 July 2015.

[3] Peace MR, Krakowiak RI, Wolf CE, Poklis A, Poklis JL (February 2017). "Identification of MDMB-FUBINACA in commercially available e-liquid formulations sold for use in electronic cigarettes". Forensic Science International. 271: 92–97. doi:10.1016/j.forsciint.2016.12.031. PMC 5511053. PMID 28076838.

[4] "Очередная жертва спайса" [Another victim of spice]. Federal Drug Control Service of the Russian Federation. 17 March 2015. Archived from the original on 14 July 2015. Retrieved 24 July 2015.

[5] "23 nya ämnen kan klassas som narkotika eller hälsofarlig vara" [23 new substances can be classified as narcotics or health hazards]. Folkhälsomyndigheten (The Public Health Authority). 1 June 2015. Retrieved 24 July 2015.

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MDMB-FUBICA

Contents

Side effects

Legality

See also

References

Legal status

Legal status	CA: Schedule II DE: NpSG (Industrial and scientific use only) UK: Class B Illegal in Sweden
Identifiers
IUPAC name methyl (2S)-2-({1-[(4-fluorophenyl)methyl]-1H-indol-3-yl}formamido)-3,3-dimethylbutanoate
CAS Number	1971007-91-6^Y
PubChem CID	129522107
ChemSpider	57621561
UNII	K53ZMB4NR6
Chemical and physical data
Formula	C₂₃H₂₅FN₂O₃
Molar mass	396.462 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES COC(=O)[C@@H](NC(=O)c1cn(Cc2ccc(F)cc2)c3ccccc13)C(C)(C)C
InChI InChI=1S/C23H25FN2O3/c1-23(2,3)20(22(28)29-4)25-21(27)18-14-26(19-8-6-5-7-17(18)19)13-15-9-11-16(24)12-10-15/h5-12,14,20H,13H2,1-4H3,(H,25,27)/t20-/m1/s1 Key:RVAWIZIGOSKPBP-HXUWFJFHSA-N