Lukaku is a surname. Notable people with the surname include:
- Roger Lukaku (born 1967), Belgian and Congolese former footballer.
- Romelu Lukaku (born 1993), Belgian footballer and son of Roger Lukaku, playing for Roma on loan from Chelsea since 2023
- Jordan Lukaku (born 1994), Belgian footballer and son of Roger Lukaku, playing for Adanaspor since 2023