This is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer. This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision. Each drug is listed once (at present), though it might fall in more than one subsection. A full alphabetical listing is included after the categorical listing.
The agents in this list are often combined into chemotherapy agent for polychemotherapy (combination chemotherapy). For example, the CHOP regimen consists of cyclophosphamide, doxorubicin, vincristine and prednisone.
Besides chemotherapy, medical oncology (pharmacotherapy for cancer) includes several noncytotoxic classes of therapy, such as hormonal therapy and targeted therapy (biologic therapy). Those agents are described in the relevant articles.
Alkylating agents edit
- Altretamine
- Bendamustine
- Busulfan
- Carboquone
- Carmustine
- Chlorambucil
- Chlormethine
- Chlorozotocin
- Cyclophosphamide
- Dacarbazine
- Fotemustine
- Ifosfamide
- Lomustine
- Melphalan
- Melphalan flufenamide
- Mitobronitol
- Nimustine
- Nitrosoureas
- Pipobroman
- Ranimustine
- Semustine
- Streptozotocin
- Temozolomide
- Thiotepa
- Treosulfan
- Triaziquone
- Triethylenemelamine
- Trofosfamide
- Uramustine
Anthracyclines edit
Aclarubicin
Cytoskeletal disruptors (taxanes) edit
Epothilones edit
Histone deacetylase inhibitors edit
Inhibitors of topoisomerase I edit
Inhibitors of topoisomerase II edit
Kinase inhibitors edit
Nucleotide analogs and precursor analogs edit
- Azacitidine
- Azathioprine
- Capecitabine
- Cytarabine
- Doxifluridine
- Fluorouracil
- Gemcitabine
- Hydroxyurea
- Mercaptopurine
- Methotrexate
- Tioguanine (formerly Thioguanine)
Peptide antibiotics edit
Platinum-based agents edit
Retinoids edit
Vinca alkaloids and derivatives edit
Full alphabetical listing edit
- Abraxane
- Actinomycin
- Alitretinoin
- All-trans retinoic acid
- Altretamine
- Azacitidine
- Azathioprine
- Belotecan
- Bendamustine
- Bexarotene
- Bleomycin
- Bortezomib
- Busulfan
- Cabazitaxel
- Camptothecin
- Carboplatin
- Carboquone
- Carmustine
- Capecitabine
- Cisplatin
- Chlorambucil
- Chlormethine
- Chlorozotocin
- Cyclophosphamide
- Cytarabine
- Dacarbazine
- Daunorubicin
- Docetaxel
- Doxifluridine
- Doxorubicin
- Epirubicin
- Epothilone
- Erlotinib
- Etoposide
- Exatecan
- Fluorouracil
- Fotemustine
- Gefitinib
- Gemcitabine
- Gimatecan
- Hydroxyurea
- Idarubicin
- Ifosfamide
- Imatinib
- Irinotecan
- Ixabepilone
- Larotaxel
- Lomustine
- Melphalan
- Melphalan flufenamide
- Mercaptopurine
- Methotrexate
- Mitobronitol
- Mitomycin C
- Mitoxantrone
- Nimustine
- Nitrosoureas
- Oxaliplatin
- Paclitaxel
- Pemetrexed
- Pipobroman
- Ranimustine
- Romidepsin
- Semustine
- Streptozotocin
- Tafluposide
- Taxotere
- Temozolomide
- Tesetaxel
- Teniposide
- Thiotepa
- Tioguanine
- Topotecan
- Treosulfan
- Tretinoin
- Triaziquone
- Triethylenemelamine
- Valrubicin
- Vemurafenib
- Vinblastine
- Vincristine
- Vindesine
- Vinorelbine
- Vismodegib
- Vorinostat