Laurence Esmonde may refer to:
- Laurence Esmonde, Lord Esmonde
- Sir Laurence Esmonde, 2nd Baronet (died 1688), of the Esmonde baronets
- Sir Laurence Esmonde, 3rd Baronet (died c. 1717), of the Esmonde baronets
- Sir Laurence Esmonde, 4th Baronet (died 1738), of the Esmonde baronets
- Sir Laurence Grattan Esmonde, 13th Baronet (1863–1943), of the Esmonde baronets
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