Leukocyte immunoglobulin-like receptor subfamily A member 4 (LILR-A5) also known as CD85 antigen-like family member G (CD85g), and immunoglobulin-like transcript 7 (ILT-7) is a protein that in humans is encoded by the LILRA4 gene.[3][4]

LILRA4
Identifiers
AliasesLILRA4, CD85g, ILT7, leukocyte immunoglobulin like receptor A4
External IDsOMIM: 607517; HomoloGene: 69118; GeneCards: LILRA4; OMA:LILRA4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_012276

n/a

RefSeq (protein)

NP_036408

n/a

Location (UCSC)Chr 19: 54.33 – 54.34 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

This gene encodes an immunoglobulin-like cell surface protein preferentially expressed in plasmacytoid dendritic cells (PDCs). This gene is highly expressed in PDCs, and is found to be rapidly down-regulated by interleukin 3 (IL3). This gene is one of the 19 highly related genes that form a leukocyte immunoglobulin-like receptor gene cluster (LRC) at chromosomal region 19q13.4.[4]

References

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  1. ^ a b c ENSG00000276798, ENSG00000274185, ENSG00000239961 GRCh38: Ensembl release 89: ENSG00000277092, ENSG00000276798, ENSG00000274185, ENSG00000239961Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Wende H, Volz A, Ziegler A (Sep 2000). "Extensive gene duplications and a large inversion characterize the human leukocyte receptor cluster". Immunogenetics. 51 (8–9): 703–13. doi:10.1007/s002510000187. PMID 10941842. S2CID 20719684.
  4. ^ a b "Entrez Gene: LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4".

Further reading

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