KFYO may refer to:

  • KFYO (AM), a radio station (790 AM/95.1 FM) licensed to Lubbock, Texas, United States
  • KZII-FM, a radio station (102.5 FM) licensed to Lubbock, Texas, United States, which used the call sign KFYO-FM from February 1985 to March 1986
  • KTTZ-TV, a television station (channel 5 analog/39 digital) licensed to Lubbock, Texas, United States, which formerly used the call sign KFYO-TV