Lysine demethylase 8 is a protein that in humans is encoded by the KDM8 gene.[5]

KDM8
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesKDM8, JMJD5, lysine demethylase 8
External IDsOMIM: 611917; MGI: 1924285; HomoloGene: 49791; GeneCards: KDM8; OMA:KDM8 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001145348
NM_024773

NM_029842

RefSeq (protein)

NP_001138820
NP_079049

NP_084118

Location (UCSC)Chr 16: 27.2 – 27.22 MbChr 7: 125.04 – 125.06 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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This gene likely encodes a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential role for this protein as a tumor suppressor. Alternatively spliced transcript variants have been described.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000155666Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030752Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Lysine demethylase 8". Retrieved 2016-04-09.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.