In molecular biology, JPX transcript, XIST activator (non-protein coding), also known as Jpx , is a long non-coding RNA. In humans, it is located on the X chromosome . It was identified during sequence analysis of the X inactivation centre, surrounding the Xist gene .[3] [4]
JPX Identifiers Aliases JPX External IDs OMIM : 300832 GeneCards : JPX Wikidata
See also
edit
References
edit
^ a b c GRCh38: Ensembl release 89: ENSG00000225470 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Chureau C, Prissette M, Bourdet A, Barbe V, Cattolico L, Jones L, et al. (2002). "Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine" . Genome Res . 12 (6): 894–908. doi :10.1101/gr.152902 . PMC 1383731 PMID 12045143 . ^ Tian D, Sun S, Lee JT (2010). "The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation" . Cell . 143 (3): 390–403. doi :10.1016/j.cell.2010.09.049 . PMC 2994261 PMID 21029862 .
Further reading
edit
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–16903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Tsuritani K, Irie T, Yamashita R, et al. (2007). "Distinct class of putative "non-conserved" promoters in humans: comparative studies of alternative promoters of human and mouse genes" . Genome Res . 17 (7): 1005–1014. doi :10.1101/gr.6030107 . PMC 1899111 PMID 17567985 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–45. doi :10.1038/ng1285 PMID 14702039 . Kolesnikov NN, Elisafenko EA (2010). "[Comparative organization and the origin of noncoding regulatory RNA genes from X-chromosome inactivation center of human and mouse]". Genetika . 46 (10): 1386–1391. PMID 21254562 .
