Medusa was the name of at least two ships of the Italian Navy and may refer to:
- Italian submarine Medusa (1911), a Medusa-class submarine launched in 1911 and sunk in 1915.
- Italian submarine Medusa (1931), an Argonauta-class submarine launched in 1931 and sunk in 1942.
This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.