The peritoneal cavity is a potential space located between the two layers of the peritoneum—the parietal peritoneum, the serous membrane that lines the abdominal wall, and visceral peritoneum, which surrounds the internal organs.[1] While situated within the abdominal cavity, the term peritoneal cavity specifically refers to the potential space enclosed by these peritoneal membranes. The cavity contains a thin layer of lubricating serous fluid that enables the organs to move smoothly against each other, facilitating the movement and expansion of internal organs during digestion.

Peritoneal cavity
Details
PrecursorIntraembryonic coelom
Identifiers
Latincavitas peritonealis,
saccus serosus peritonei
MeSHD010529
TA98A10.1.02.001
TA23702
THH3.04.08.0.00011
FMA14704
Anatomical terminology

The parietal and visceral peritonea are named according to their location and function. The peritoneal cavity, derived from the coelomic cavity in the embryo, is one of several body cavities, including the pleural cavities surrounding the lungs and the pericardial cavity around the heart.

The peritoneal cavity is the largest serosal sac and fluid-filled cavity in the body,[2] it secretes approximately 50 milliliters (1.7 U.S. fl oz) of fluid daily. This fluid serves as a lubricant and has anti-inflammatory properties. The cavity is divided into the greater and lesser sacs, with the greater sac further subdivided into the supracolic and infracolic compartments.[3][4]

Compartments

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The peritoneal cavity is divided into the greater and lesser sacs. The greater sac comprises the majority of the peritoneal cavity, while the lesser sac, also known as the omental bursa, is smaller and situated posterior to the stomach and lesser omentum. They are connected by the omental foramen.[4]

The greater sac is further subdivided into two compartments by the mesentery of the transverse colon, known as the transverse mesocolon. This division creates an upper and a lower compartment within the greater sac, named the supracolic and infracolic compartment respectively, each housing different organs and structures of the abdominal cavity.[3][4]

The liver, spleen, stomach, and lesser omentum are contained within the supracolic compartment. The small intestine surrounded by the ascending, transverse, and descending colon, and the paracolic gutters are contained within the infracolic compartment.

Clinical significance

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The peritoneal cavity is widely used in intraperitoneal injections to administer chemotherapy drugs,[5][6] and is also utilized in peritoneal dialysis.[7] An increase in capillary pressure in the abdominal organs can cause fluid to leave the interstitial space and enter the peritoneal cavity, resulting in a condition called ascites. When cerebrospinal fluid overaccumulates, such as in hydrocephalus, the fluid is commonly diverted intentionally to the peritoneal cavity using a surgically placed cerebral shunt.[8] Sampling of body fluid from the peritoneal cavity is referred to as peritoneocentesis.

See also

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References

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  1. ^ Pannu, HK; Oliphant, M (October 2015). "The subperitoneal space and peritoneal cavity: basic concepts". Abdominal Imaging. 40 (7): 2710–22. doi:10.1007/s00261-015-0429-5. PMC 4584112. PMID 26006061.
  2. ^ Heimbürger, Olof (1 January 2019). "29 - Peritoneal Physiology". Chronic Kidney Disease, Dialysis, and Transplantation (Fourth Edition). Elsevier: 450–469.e6. doi:10.1016/b978-0-323-52978-5.00029-x. ISBN 9780323529785.
  3. ^ a b Sharma, M; Madambath, JG; Somani, P; Pathak, A; Rameshbabu, CS; Bansal, R; Ramasamy, K; Patil, A (March 2017). "Endoscopic ultrasound of peritoneal spaces". Endoscopic Ultrasound. 6 (2): 90–102. doi:10.4103/2303-9027.204816. PMC 5418973. PMID 28440234.
  4. ^ a b c "The Peritoneal Cavity - Greater Sac - Lesser Sac - TeachMeAnatomy". teachmeanatomy.info. Retrieved 2024-09-29.
  5. ^ Yu, Wansik (2003-07-01). "Impact of perioperative intraperitoneal chemotherapy on the treatment of primary gastric cancer". Surgical Oncology Clinics of North America. 12 (3): 623–634. doi:10.1016/S1055-3207(03)00025-5. ISSN 1055-3207.
  6. ^ Swart, A.M.C.; Burdett, S.; Ledermann, J.; Mook, P.; Parmar, M.K.B. (2008). "Why i.p. therapy cannot yet be considered as a standard of care for the first-line treatment of ovarian cancer: a systematic review". Annals of Oncology. 19 (4): 688–695. doi:10.1093/annonc/mdm518. ISSN 0923-7534.
  7. ^ De Vin, Filip; Rutherford, Peter; Faict, Dirk (January 2009). "Intraperitoneal Administration of Drugs in Peritoneal Dialysis Patients: A Review of Compatibility and Guidance for Clinical Use". Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis. 29 (1): 5–15. doi:10.1177/089686080902900101. ISSN 0896-8608.
  8. ^ Adzick, Scott; Thom, Spong; Brock, Burrows; et al. (17 March 2011). "A Randomized Trial of Prenatal versus Postnatal Repair of Myelomeningocele". The New England Journal of Medicine. 364 (11): 993–1004. doi:10.1056/nejmoa1014379. PMC 3770179. PMID 21306277.
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  • peritoneum at The Anatomy Lesson by Wesley Norman (Georgetown University)