Homofentanyl (N-Phenylpropylnorfentanyl, Fentanyl propyl analogue) is an opioid derivative which has been sold as a designer drug. It is a homologue of fentanyl, with similar analgesic and sedative effects but lower potency,[1][2] around 14× stronger than pethidine.[3]

Homofentanyl
Identifiers
  • N-phenyl-N-[1-(3-phenylpropyl)piperidin-4-yl]propanamide
CAS Number
PubChem CID
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC23H30N2O
Molar mass350.506 g·mol−1
3D model (JSmol)
  • CCC(=O)N(C1CCN(CC1)CCCC2=CC=CC=C2)C3=CC=CC=C3
  • InChI=1S/C23H30N2O/c1-2-23(26)25(21-13-7-4-8-14-21)22-15-18-24(19-16-22)17-9-12-20-10-5-3-6-11-20/h3-8,10-11,13-14,22H,2,9,12,15-19H2,1H3
  • Key:CKBFKWWOUYBCRH-UHFFFAOYSA-N

See also

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References

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  1. ^ Cooper D, Jacob M, Allen A (April 1986). "Identification of fentanyl derivatives". Journal of Forensic Sciences. 31 (2): 511–28. doi:10.1520/JFS12283J. PMID 3711827.
  2. ^ "Fentanyl-Related Substances with no Currently Known Legitimate Uses" (PDF). International Narcotics Control Board (INCB). 15 September 2020.
  3. ^ Casy AF, Parfitt RY (1986). Opioid analgesics, chemistry and receptors. New York: Plenum Press. p. 289. ISBN 978-0-306-42130-3.