Holbrook is a masculine given name and a surname. It may refer to:

Surname

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Given name

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  • Holbrook Blinn (1872–1928), American stage and film actor
  • Holbrook Gaskell (1813–1909), British industrialist
  • Holbrook Jackson (1874–1948), British journalist, writer and publisher
  • Holbrook Working (1895–1985), American professor of economics and statistics at Stanford University’s Food Research Institute