Henry Kane may refer to:
- Henry Kane (Poltergeist), a character in the film series Poltergeist
- Henry B. Kane (1902–1971), American illustrator, photographer, and author of nature books for children
- Henry Coey Kane (died 1917), Royal Navy officer
- Henry Plow Kane (1825-1893), founding headmaster at Launceston Church Grammar School, Tasmania, Australia