Harley H. McAdams (born 1938, Liberty, Texas) is an American physicist, microbial geneticist, and developmental biologist. McAdams and his collaborators have published foundational insights on the nature of genetic regulatory logic and cell biology,[1][2][3] the molecular basis for inevitable random variation levels of protein production between different cells,[4][5] and genetic logic circuits that control the bacterial cell cycle.[6][7] McAdams is married to Lucy Shapiro. They were jointly awarded the 2009 John Scott Medal for “bringing the methods of electrical circuit analysis to the description of genetic networks of the simple bacterium Caulobacter.”[8]
Harley McAdams | |
|---|---|
| Born | 1938 (age 85–86) |
| Nationality | American |
| Occupation(s) | Professor of Developmental Biology Microbial geneticist Physicist |
| Spouse | Lucy Shapiro |
McAdams, a professor emeritus in the Department of Developmental Biology in the Stanford University School of Medicine, holds undergraduate and graduate degrees in physics from Texas A&M University (BS), the University of Illinois (Urbana) (MS), and Rice University (MA, PhD). He is a fellow of the American Society for Microbiology.[9]
References edit
- ^ McAdams, H. H.; Shapiro, L. (1995). "Circuit simulation of genetic networks". Science. 269 (5224): 650–6. Bibcode:1995Sci...269..650M. doi:10.1126/science.7624793. PMID 7624793.
- ^ Arkin, A.; Ross, J.; McAdams, H. H. (1998). "Stochastic kinetic analysis of developmental pathway bifurcation in phage lambda-infected Escherichia coli cells". Genetics. 149 (4): 1633–48. doi:10.1093/genetics/149.4.1633. PMC 1460268. PMID 9691025.
- ^ McAdams, H. H.; Arkin, A. (1998). "Simulation of prokaryotic genetic circuits". Annual Review of Biophysics and Biomolecular Structure. 27: 199–224. doi:10.1146/annurev.biophys.27.1.199. PMID 9646867.
- ^ McAdams, H. H.; Arkin, A. (1999). "It's a noisy business! Genetic regulation at the nanomolar scale". Trends Genet. 15 (2): 65–69. doi:10.1016/S0168-9525(98)01659-X. PMID 10098409.
- ^ McAdams, H. H.; Arkin, A. (1997). "Stochastic mechanisms in gene expression". Proc. Natl. Acad. Sci. U.S.A. 94 (3): 814–9. Bibcode:1997PNAS...94..814M. doi:10.1073/pnas.94.3.814. PMC 19596. PMID 9023339.
- ^ McAdams, H. H.; Shapiro, L. (2009). "System-level design of bacterial cell cycle control". FEBS Lett. 586 (2): 3984–3991. doi:10.1016/j.febslet.2009.09.030. PMC 2795017. PMID 19766635.
- ^ McAdams, H. H.; Shapiro, L. (2003). "A bacterial cell-cycle regulatory network operating in time and space". Science. 301 (5641): 3984–3991. Bibcode:2003Sci...301.1874M. doi:10.1126/science.1087694. PMID 14512618. S2CID 28742912.
- ^ "The John Scott Award".
- ^ "Stanford Profile, Harley H McAdams".
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