major histocompatibility complex (human), class I, B56
Alleles B*5601, *5602, *5603, *5604
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*5601
B*5602
B*5603
B*5604
Locus chr.6 6p21.31

HLA-B56 (B56) is an HLA-B serotype. B56 is a split antigen from the B22 broad antigen, sister serotypes are B54 and B55. The serotype identifies the more common HLA-B*56 gene products.[1] (For terminology help see: HLA-serotype tutorial)

Serotype

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B56 and B22 serotype recognition of Some HLA B*56 allele-group gene products[2]
B*56 B56 B22 Sample
allele % % size (N)
5601 72 5 671
5603 46 8 13
5604 73 11

Allele distribution

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HLA B*5601 frequencies
freq
ref. Population (%)
[3] Australian Aborigine Kimberly 35.5
[3] Papua New Guinea Madang 34.6
[3] Papua New Guinea New Britain Rabaul 31.6
[3] Taiwan Ami 20.4
[3] New Caledonia 19.2
[3] Australian Aborigine Groote Eylandt 18.0
[3] Australian Aborigine Cape York Peninsula 16.5
[3] Australian Aborigine Yuendumu 11.4
[3] China Yunnan Lisu 9.4
[3] China Yunnan Nu 3.8
[3] Senegal Niokholo Mandenka 2.7
[3] Sudanese 2.5
[3] American Samoa 2.0
[3] China Guangxi Maonan 1.9
[3] Taiwan Hakka 1.8
[3] Thailand 1.8
[3] Finland 1.7
[3] Georgia Tbilisi Kurds 1.7
[3] India Andhra Pradesh Golla 1.4
[3] Croatia 1.3
[3] Japan (5) 1.3
[3] South Africa Natal Tamil 1.0
[3] Taiwan Rukai 1.0

References

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  1. ^ Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
  2. ^ derived from IMGT/HLA
  3. ^ a b c d e f g h i j k l m n o p q r s t u v w Middleton, D.; Menchaca, L.; Rood, H.; Komerofsky, R. (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–407. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.