Heme binding protein 1 is a protein that in humans is encoded by the HEBP1 gene.[5]

HEBP1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesHEBP1, HBP, HEBP, heme binding protein 1
External IDsOMIM: 605826; MGI: 1333880; HomoloGene: 8407; GeneCards: HEBP1; OMA:HEBP1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015987

NM_013546

RefSeq (protein)

NP_057071

NP_038574

Location (UCSC)Chr 12: 12.97 – 13 MbChr 6: 135.11 – 135.18 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000013583Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042770Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: Heme binding protein 1".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.