H2A histone family, member B3 is a protein that in humans is encoded by the H2AFB3 gene.[5]

H2AB3
Identifiers
AliasesH2AB3, H2ABBD, H2AFB, H2A histone family member B3, H2A.B variant histone 3, H2AFB3, H2AB2, H2A.B.1
External IDsOMIM: 300445; MGI: 3644980; HomoloGene: 129517; GeneCards: H2AB3; OMA:H2AB3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_080720

NM_001281530

RefSeq (protein)

NP_001017991

NP_001268459

Location (UCSC)Chr X: 155.46 – 155.46 MbChr X: 115.59 – 115.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the most telomeric copy. [provided by RefSeq, Jul 2008].[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000277745Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000082482Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: H2A histone family, member B3". Retrieved 2012-03-12.

Further reading

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