As a nickname, Guitar may refer to:

  • Guitar Gable (1937–2017), American Louisiana blues, swamp blues and swamp pop musician
  • Guitar Gabriel (1925–1996), American blues musician whose unique style has been referred to as "Toot Blues"
  • Guitar Nubbit (1923–1995), American blues guitarist and singer most notable for "Georgia Chain Gang"
  • Guitar Shorty (1934–2022), American blues guitarist, singer and songwriter known for his style and stage antics
  • Guitar Slim (1926–1959), American blues guitarist in the 1940s and 1950s, best known for the million-selling song "The Things That I Used to Do"
  • Guitar Slim Jr. (born 1952), American New Orleans blues guitarist and singer
  • Johnny "Guitar" Watson (1935–1996), American blues / funk guitarist, best known for chart single "A Real Mutha for Ya".

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