Gugulethu is a township in South Africa. Gugulethu may also refer to:
- Gugulethu Mayisela (born 2004), South African model
- Gugulethu Sophia Mbatha (born 1983), English actress
- Gugulethu Zuma-Ncube (born 1985), South African producer and actress
- Gugulethu Seven, anti-apartheid group killed by South African Police in 1986
- Gugulethu massacre, mass shooting in November 2020
This disambiguation page lists articles associated with the title Gugulethu.
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