Grifolin is an isolate of the mushroom Albatrellus confluens which upregulates DAPK1 in vitro.[1]
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Preferred IUPAC name
5-Methyl-2-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]benzene-1,3-diol | |
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3D model (JSmol)
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ChEMBL | |
ChemSpider | |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C22H32O2 | |
Molar mass | 328.496 g·mol−1 |
Melting point | 41 °C (106 °F; 314 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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References
edit- ^ Luo, XJ; Li, LL; Deng, QP; Yu, XF; Yang, LF; Luo, FJ; Xiao, LB; Chen, XY; Ye, M; Liu, JK; Cao, Y (2011). "Grifolin, a potent antitumour natural product upregulates death-associated protein kinase 1 DAPK1 via p53 in nasopharyngeal carcinoma cells". European Journal of Cancer. 47 (2): 316–25. doi:10.1016/j.ejca.2010.09.021. PMID 20943371.