Great Void can refer to:
- Astronomy
- A "super void", large empty regions of spaces
- Boötes Void, a supervoid in Bootes constellation
- Giant Void, a supervoid in the Canes Venatici constellation
- CMB cold spot, a supervoid in Eridanus constellation
- Outer space in general
- Other
- At the Edge of the Great Void, the nineteenth volume of the Valérian and Laureline series
- A region in the Crystalicum RPG card game
- "Eoarchaean: The Great Void", a song by The Ocean Collective, from the album Precambrian
- Greetings from the Great Void, an album from the Italian duo My Cat Is an Alien
- Purgatory in the after-life
This disambiguation page lists articles associated with the title Great void.
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