Glycoside hydrolase family 101

In molecular biology, glycoside hydrolase family 101 is a family of glycoside hydrolases.

Endo-alpha-N-acetylgalactosaminidase
Identifiers
SymbolGlyco_hydro_101
PfamPF12905
Pfam clanCL0058
CAZyGH101
CDDcd14244
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
Glycoside hydrolases related to GH101 family
Identifiers
SymbolGHL
PfamPF11308
Pfam clanCL0058
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.[1][2][3] This classification is available on the CAZy web site,[4][5] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.[6][7]

Glycoside hydrolase family GH101 includes enzymes with endo-α-N-acetylgalactosaminidase EC 3.2.1.97 activity and can be split into several subfamilies.[8]

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References

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  1. ^ Henrissat B, Callebaut I, Mornon JP, Fabrega S, Lehn P, Davies G (1995). "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proc. Natl. Acad. Sci. U.S.A. 92 (15): 7090–7094. Bibcode:1995PNAS...92.7090H. doi:10.1073/pnas.92.15.7090. PMC 41477. PMID 7624375.
  2. ^ Henrissat B, Davies G (1995). "Structures and mechanisms of glycosyl hydrolases". Structure. 3 (9): 853–859. doi:10.1016/S0969-2126(01)00220-9. PMID 8535779.
  3. ^ "Bairoch, A. "Classification of glycosyl hydrolase families and index of glycosyl hydrolase entries in SWISS-PROT". 1999". Archived from the original on 2011-05-25. Retrieved 2011-10-05.
  4. ^ "Home". CAZy.org. Retrieved 2018-03-06.
  5. ^ Lombard, Vincent; Golaconda Ramulu, Hemalatha; Drula, Elodie; Coutinho, Pedro M.; Henrissat, Bernard (2014-01-01). "The carbohydrate-active enzymes database (CAZy) in 2013". Nucleic Acids Research. 42 (D1): D490–D495. doi:10.1093/nar/gkt1178. ISSN 0305-1048. PMC 3965031. PMID 24270786.
  6. ^ "Glycoside Hydrolase Family 101". CAZypedia.org. Retrieved 2018-03-06.
  7. ^ CAZypedia Consortium (2018-12-01). "Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes" (PDF). Glycobiology. 28 (1): 3–8. doi:10.1093/glycob/cwx089. hdl:21.11116/0000-0003-B7EB-6. ISSN 1460-2423. PMID 29040563.
  8. ^ Naumoff DG (2010). "GH101 family of glycoside hydrolases: subfamily structure and evolutionary connections with other families". J Bioinform Comput Biol. 8 (3): 437–451. doi:10.1142/s0219720010004628. PMID 20556855.