GSDMC

Gasdermin C is a protein that in humans is encoded by the GSDMC gene.

GSDMC
Identifiers
Aliases	GSDMC, MLZE, gasdermin C
External IDs	OMIM: 608384 MGI: 2146102 HomoloGene: 69487 GeneCards: GSDMC
Gene location (Mouse) Chr. Chromosome 15 (mouse) Band 15|15 D1 Start 63,696,195 bp End 63,717,026 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in zone of skin skin of abdomen spleen vagina skeletal muscle tissue minor salivary glands gastrocnemius muscle left ventricle thymus urinary bladder Top expressed in medullary collecting duct left colon secondary oocyte crypt of lieberkuhn of small intestine jejunum stomach epithelium of stomach morula ileum cardia More reference expression data BioGPS n/a
Gene ontology Molecular function molecular function phosphatidylserine binding phosphatidylinositol-4,5-bisphosphate binding phosphatidylinositol-4-phosphate binding Cellular component cytoplasm mitochondrion microtubule organizing center cytosol plasma membrane membrane Biological process programmed cell death biological process pyroptosis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 56169 331063 Ensembl n/a ENSMUSG00000056293 UniProt Q9BYG8 Q2KHK6 RefSeq (mRNA) NM_031415 NM_001168274 NM_177912 RefSeq (protein) NP_113603 NP_001161746 NP_808580 Location (UCSC) n/a Chr 15: 63.7 – 63.72 Mb PubMed search
Wikidata
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Further reading

• Saeki N, Usui T, Aoyagi K, Kim DH, Sato M, Mabuchi T, Yanagihara K, Ogawa K, Sakamoto H, Yoshida T, Sasaki H (2009). "Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium". Genes Chromosomes Cancer. 48 (3): 261–71. doi:10.1002/gcc.20636. PMID 19051310. S2CID 19705164.