GTPase IMAP family member 4 is an enzyme that in humans is encoded by the GIMAP4 gene.[4][5][6]

GIMAP4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesGIMAP4, IAN-1, IAN1, IMAP4, MSTP062, GTPase, IMAP family member 4
External IDsOMIM: 608087; MGI: 1349656; HomoloGene: 75084; GeneCards: GIMAP4; OMA:GIMAP4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_018326
NM_001363532

NM_001243199
NM_001243200
NM_001243201
NM_174990
NM_175048

RefSeq (protein)

NP_060796
NP_001350461

NP_001230128
NP_001230129
NP_001230130
NP_778155
NP_778213

Location (UCSC)n/aChr 6: 48.66 – 48.67 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The encoded protein of this gene may be negatively regulated by T-cell acute lymphocytic leukemia 1 (TAL1). In humans, the IAN subfamily genes are located in a cluster at 7q36.1.[6]

References

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  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000054435Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Krucken J, Schroetel RM, Muller IU, Saidani N, Marinovski P, Benten WP, Stamm O, Wunderlich F (Oct 2004). "Comparative analysis of the human gimap gene cluster encoding a novel GTPase family". Gene. 341: 291–304. doi:10.1016/j.gene.2004.07.005. PMID 15474311.
  5. ^ Filen JJ, Filen S, Moulder R, Tuomela S, Ahlfors H, West A, Kouvonen P, Kantola S, Bjorkman M, Katajamaa M, Rasool O, Nyman TA, Lahesmaa R (Jan 2009). "Quantitative proteomics reveals GIMAP family proteins 1 and 4 to be differentially regulated during human T helper cell differentiation". Mol Cell Proteomics. 8 (1): 32–44. doi:10.1074/mcp.M800139-MCP200. PMC 2621005. PMID 18701445.
  6. ^ a b "Entrez Gene: GIMAP4 GTPase, IMAP family member 4".

Further reading

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