RAC/CDC42 exchange factor, also known as GEFT, is a human gene.[5]

ARHGEF25
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesARHGEF25, GEFT, p63RhoGEF, Rho guanine nucleotide exchange factor 25
External IDsOMIM: 610215; MGI: 1277173; HomoloGene: 32691; GeneCards: ARHGEF25; OMA:ARHGEF25 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001111270
NM_133483
NM_182947
NM_001347933

NM_001166413
NM_028027
NM_001358557
NM_001358558

RefSeq (protein)

NP_001104740
NP_891992
NP_001334862

NP_001159885
NP_082303
NP_001345486
NP_001345487

Location (UCSC)Chr 12: 57.61 – 57.62 MbChr 10: 127.02 – 127.03 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

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GEFT has been shown to interact with RHOA.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000240771Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000019467Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: GEFT RAC/CDC42 exchange factor".
  6. ^ Lutz S, Freichel-Blomquist A, Rümenapp U, Schmidt M, Jakobs KH, Wieland T (May 2004). "p63RhoGEF and GEFT are Rho-specific guanine nucleotide exchange factors encoded by the same gene". Naunyn-Schmiedeberg's Arch. Pharmacol. 369 (5): 540–6. doi:10.1007/s00210-004-0926-5. PMID 15069594. S2CID 19812449.

Further reading

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