Fusobacteriales-1 RNA motif

The Fusobacteriales-1 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] Fusobacteriales-1 motif RNAs are found in Fusobacteriales.

Fusobacteriales-1
Consensus secondary structure and sequence conservation of Fusobacteriales-1 RNA
Identifiers
SymbolFusobacteriales-1
RfamRF02920
Other data
RNA typeCis-reg
SOSO:0005836
PDB structuresPDBe

Most Fusobacteriales-1 RNAs are located upstream of genes homologous to the locus FSAG_00736, which encodes a hypothetical protein in Fusobacterium peridonticum. However, some Fusobacteriales-1 RNAs are located upstream of genes that do not appear to be homologous to FSAG_00736. Additionally 1 Fusobacteriales-1 RNAs is not found upstream of a protein-coding gene. In view of this information, it is ambiguous whether Fusobacteriales-1 RNAs function as cis-regulatory elements or whether they operate in trans.

References

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  1. ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.