Francesco Barberini may refer to:
- Francesco Barberini (died 1600), uncle of Pope Urban VIII and the subject of the Bust of Francesco Barberini
- Francesco Barberini (1597–1679), Cardinal-nephew of Pope Urban VIII from 1623
- Francesco Barberini (1662–1738), Cardinal from 1690
This disambiguation page lists articles about people with the same name.
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