Fluoroacetamide

Fluoroacetamide
Names
	IUPAC name 2-Fluoroacetamide
Identifiers
CAS Number	640-19-7 ;
3D model (JSmol)	Interactive image; Interactive image;
ChEBI	CHEBI:53124 ;
ChEMBL	ChEMBL160811 ;
ChemSpider	12025 ;
ECHA InfoCard	100.010.331
KEGG	C18675 ;
PubChem CID	12542;
UNII	B18R611M38 ;
CompTox Dashboard (EPA)	DTXSID2034255 ;
	InChI InChI=1S/C2H4FNO/c3-1-2(4)5/h1H2,(H2,4,5) Key: FVTWJXMFYOXOKK-UHFFFAOYSA-N ; InChI=1/C2H4FNO/c3-1-2(4)5/h1H2,(H2,4,5) Key: FVTWJXMFYOXOKK-UHFFFAOYAA;
	SMILES C(C(=O)N)F; FCC(=O)N;
Properties
Chemical formula	FCH2CONH2
Molar mass	77.058 g·mol−1
Appearance	Colorless crystals
Melting point	107 to 109 °C (225 to 228 °F; 380 to 382 K)
Solubility in water	Soluble
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	Very toxic
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H300+H310
Precautionary statements	P262, P264, P270, P280, P301+P310+P330, P302, P350, P362, P405, P501
NFPA 704 (fire diamond)	4 1
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	80 mg/kg (dermal, rat)
LC50 (median concentration)	550 mg/m3(mouse, inhalation, dust/mist)
Safety data sheet (SDS)
Related compounds
Related compounds	Chloroacetamide; Bromoacetamide; Iodoacetamide; Fluoroacetic acid; Acetamide;
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Fluoroacetamide is an organic compound with the chemical formula F C H₂CO NH₂. It is a compound based on acetamide with one fluorine atom replacing hydrogen on the methyl group. It is very toxic.^[1] It is a metabolic poison which disrupts the citric acid cycle and was used as a rodenticide.^[2] May cause reproductive disorders. If swallowed or in contact with skin, it can cause serious damage and death. Can cause serious eye damage.^[1]

References

^ ^a ^b ^c https://www.sigmaaldrich.com/US/en/sds/aldrich/128341?userType=anonymous ^{[bare URL]}
^ MATSUMURA F, O'BRIEN RD. A COMPARATIVE STUDY OF THE MODES OF ACTION OF FLUOROACETAMIDE AND FLUOROACETATE IN THE MOUSE AND AMERICAN COCKROACH. Biochem Pharmacol. 1963 Oct;12:1201-5.doi:10.1016/0006-2952(63)90095-9 PMID 14074120

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