Flight 422 may refer to:
- Air France Flight 422, a flight which crashed near Bogotá, Colombia, in 1998
- Kuwait Airways Flight 422, a flight hijacked over the Gulf of Oman in 1988, leading to one of the longest skyjackings on record
- Merpati Nusantara Airlines Flight 422, a 1994 flight that overshot the runway at Indonesia's Achmad Yani International Airport
This disambiguation page lists articles associated with the title Flight 422.
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