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Summary
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English: Moco biosynthetic pathway in bacteria and humans. Molybdenum cofactor (Moco) biosynthesis occurs in four steps: (i) the radical-mediated cyclization of nucleotide, guanosine 5'-triphosphate (GTP), to (8S)‑3 ́,8‐cyclo‑7,8‑dihydroguanosine 5 ́‑triphosphate (3 ́,8‑cH2GTP), (ii) the formation of cyclic pyranopterin monophosphate (cPMP) from the 3 ́,8‑cH2GTP, (iii) the conversion of cPMP into molybdopterin (MPT), (iv) the insertion of molybdate into MPT to form Moco. The human enzymes are indicated in parenthesis. |
| Date | |
| Source | Own work |
| Author | Jonaswakefield54 |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 19:14, 16 May 2015 |  | 729 × 1,831 (42 KB) | Jonaswakefield54 | User created page with UploadWizard |
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