Forkead box I3 (FOXI3) is a protein that in humans is encoded by the FOXI3 gene. FOXI3 is a forkhead box transcription factor that is expressed in the development of hair and teeth. One of its mutations is a dominant allele responsible for the heterozygous Hh hairless trait in dogs. It was identified in 2008.[5]

FOXI3
Identifiers
AliasesFOXI3, forkhead box I3
External IDsOMIM: 612351; MGI: 3511278; HomoloGene: 52949; GeneCards: FOXI3; OMA:FOXI3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001135649

NM_001101464

RefSeq (protein)

NP_001129121

n/a

Location (UCSC)Chr 2: 88.45 – 88.45 MbChr 6: 70.93 – 70.94 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

See also

edit

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000214336Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000055874Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Drögemüller C, Karlsson EK, Hytönen MK, Perloski M, Dolf G, Sainio K, et al. (September 2008). "A mutation in hairless dogs implicates FOXI3 in ectodermal development". Science. 321 (5895): 1462. Bibcode:2008Sci...321.1462D. doi:10.1126/science.1162525. PMID 18787161. S2CID 206514824.