Fibronectin leucine-rich repeat transmembrane protein FLRT2 is a protein that in humans is encoded by the FLRT2 gene.[5][6][7]

FLRT2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesFLRT2, fibronectin leucine rich transmembrane protein 2
External IDsOMIM: 604807; MGI: 3603594; HomoloGene: 8291; GeneCards: FLRT2; OMA:FLRT2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001346143
NM_001346144
NM_001346145
NM_001346146
NM_013231

NM_201518

RefSeq (protein)

NP_001333072
NP_001333073
NP_001333074
NP_001333075
NP_037363

NP_958926

Location (UCSC)Chr 14: 85.53 – 85.65 MbChr 12: 95.66 – 95.75 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRT family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000185070Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000047414Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Lacy SE, Bönnemann CG, Buzney EA, Kunkel LM (December 1999). "Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins". Genomics. 62 (3): 417–26. doi:10.1006/geno.1999.6033. PMID 10644439.
  6. ^ Haines BP, Wheldon LM, Summerbell D, Heath JK, Rigby PW (September 2006). "Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development". Developmental Biology. 297 (1): 14–25. doi:10.1016/j.ydbio.2006.04.004. PMID 16872596.
  7. ^ a b "Entrez Gene: FLRT2 fibronectin leucine rich transmembrane protein 2".

Further reading

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