Expressome may refer to:
- A supramolecular complex consisting of RNA polymerase and a trailing ribosome linked by a shared mRNA. The expressome complex mediates a mechanism of gene expression regulation termed transcription-translation coupling.[1][2][3]
- The whole set of gene expression in a cell, tissue, organ, organisms, and species. Expressome is a slightly larger concept than transcriptome. The transcriptome is the set of transcripts, while expressome includes transcripts, proteins and other ligands (abundance or concentration).
See also edit
External links edit
References edit
- ^ Kohler, R.; Mooney, R. A.; Mills, D. J.; Landick, R. & Cramer, P. (2017). "Architecture of a transcribing-translating expressome". Science. 356 (6334): 194–197. Bibcode:2017Sci...356..194K. doi:10.1126/science.aal3059. PMC 5528865. PMID 28408604.
- ^ Webster, M. W.; Takacs, M.; Zhu, C.; Vidmar, V.; Eduljee, A.; Abdelkareem, M. & Weixlbaumer, A. (2020). "Structural basis of transcription-translation coupling and collision in bacteria". Science. 369 (6509): 1355–1359. Bibcode:2020Sci...369.1355W. doi:10.1126/science.abb5036. PMID 32820062. S2CID 221222557.
- ^ O'Reilly, F. J.; Xue, L.; Graziadei, A.; Sinn, L.; Lenz, S.; Tegunov, D.; Blötz, C.; Singh, N.; Hagen, W.; Cramer, P.; Stülke, J.; Mahamid, J. & Rappsilber, J. (2020). "In-cell architecture of an actively transcribing-translating expressome". Science. 369 (6503): 554–557. Bibcode:2020Sci...369..554O. doi:10.1126/science.abb3758. hdl:21.11116/0000-0006-D30E-D. PMC 7115962. PMID 32732422.
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