epi-Cedrol synthase (EC 4.2.3.39, 8-epicedrol synthase, epicedrol synthase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (8-epi-cedrol-forming).[1][2] This enzyme catalyses the following chemical reaction

epi-cedrol synthase
Identifiers
EC no.4.2.3.39
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
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NCBIproteins
(2E,6E)-farnesyl diphosphate + H2O 8-epi-cedrol + diphosphate

This enzyme is activated by Mg2+.

References

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  1. ^ Mercke P, Crock J, Croteau R, Brodelius PE (September 1999). "Cloning, expression, and characterization of epi-cedrol synthase, a sesquiterpene cyclase from Artemisia annua L". Archives of Biochemistry and Biophysics. 369 (2): 213–22. doi:10.1006/abbi.1999.1358. PMID 10486140.
  2. ^ Hua L, Matsuda SP (September 1999). "The molecular cloning of 8-epicedrol synthase from Artemisia annua". Archives of Biochemistry and Biophysics. 369 (2): 208–12. doi:10.1006/abbi.1999.1357. PMID 10486139.
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