Eastside High School or East Side High School can refer to:
- East Side High School (Cleveland, Mississippi)
- Eastside High School (Coeburn, Virginia)
- Eastside High School (Covington, Georgia)
- Eastside High School (Gainesville, Florida)
- Eastside High School (Lancaster, California)
- Eastside High School (Sacramento, California)
- Eastside High School (Madison, Wisconsin)
- East Side High School (Newark, New Jersey)
- Eastside High School (Paterson, New Jersey), highlighted in the 1989 film Lean on Me
- Eastside High School (Taylors, South Carolina)
- Eastside Junior-Senior High School (Butler, Indiana)
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