E51 may refer to:
- Nokia E51, a Symbian OS smartphone
- HMS E51, a British E class submarine
- European route E51, a road connecting Berlin and Nuremberg in Germany
- Nimzo-Indian Defence, Encyclopaedia of Chess Openings code
- Higashi-Kantō Expressway, route E51 in Japan
This disambiguation page lists articles associated with the same title formed as a letter–number combination.
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