Nikhil C Munshi (born 1957) is an American hematologist and oncologist and professor at Harvard Medical School.[1]

Life and education

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Nikhil Munshi was born in India and received his medical degree from the S.S.G. Hospital and M.S. University, Baroda India in 1984. From 1986-1987, he completed a Research Fellowship in Medical Oncology at the Johns Hopkins Oncology Center in Baltimore, Maryland. In 1987-1992 he completed a clinical fellowship in hematology/oncology at the Indiana University Medical Center. He began working at the University of Arkansas for Medical Sciences in 1992, where he served as Associate Professor. From 1996-2001, he served as the Director of the Clinical Gene Transduction Laboratory and became Professor of Medicine.

In 2001, he was appointed the Associate Director of the Jerome Lipper Myeloma Center at the Dana Farber Cancer Institute, which is part of Harvard Medical School. In 2013, he was named the Director, Basic and correlative Science, at the Jerome Lipper Myeloma Center. In 2014, he was made a Professor of Medicine at Harvard Medical School. In 2019, he became the first Kraft Family Chair. In addition to his activities at Harvard, since 2006, he has served as the chair of the National Myeloma Initiative at VA. From 2010-2016, he was Chairman of the Myeloma Steering Committee for the National Cancer Institute.

Scientific work and research activities

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Munshi is considered one of the world’s leading experts in the field of multiple myeloma. Dr. Munshi’s research focus spans both basic sciences to understand genomic changes in myeloma[2] and elucidate molecular mechanisms driving the genomic instability in cancer[3], to translational approaches directed at improving diagnosis and prognosis as well as therapeutics[4]. Dr Munshi’s clinical interests include CAR T-cell therapy in multiple myeloma and developing novel targeted therapeutics including novel antigen-directed and immune effector cell therapy/vaccine approaches.[5][6]

Honors and accolades

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  • Member NIH study section - Experimental Immunology
  • Member American Society of Hematology Scientific sub-committee, Hematopoietic Signaling 2001-2009
  • Chairman, ASH Scientific Session 1999, 2000, 2001, 2003
  • Leukemia Society Scholar in clinical Research award
  • American Cancer Society Research Institutional Grant
  • American Society of Clinical Oncology Young Investigator Award
  • American Society of Clinical Oncology Travel Award
  • National Cancer Institute Institutional Training fellowship
  • Waldenstrom’s Award for life time Achievement in Myeloma Research, International Myeloma Society, 2013
  • B.C. Roy Award, President of India for outstanding achievement in medical research, 2016
  • Member, American Association of Physician, 2017
  • President of the International Myeloma Society, 2019-2023

References

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  1. ^ "Nikhil C. Munshi, MD".
  2. ^ Bolli, N.; Maura, F.; Minvielle, S.; Gloznik, D.; Szalat, R.; Fullam, A.; Martincorena, I.; Dawson, K. J.; Samur, M. K.; Zamora, J.; Tarpey, P.; Davies, H.; Fulciniti, M.; Shammas, M. A.; Tai, Y. T.; Magrangeas, F.; Moreau, P.; Corradini, P.; Anderson, K.; Alexandrov, L.; Wedge, D. C.; Avet-Loiseau, H.; Campbell, P.; Munshi, N. (2018). "Genomic patterns of progression in smoldering multiple myeloma". Nature Communications. 9 (1): 3363. Bibcode:2018NatCo...9.3363B. doi:10.1038/s41467-018-05058-y. PMC 6105687. PMID 30135448.
  3. ^ "Targeting genomic instability and evolution in myeloma".
  4. ^ Munshi, N. C.; Anderson Jr, L. D.; Shah, N.; Madduri, D.; Berdeja, J.; Lonial, S.; Raje, N.; Lin, Y.; Siegel, D.; Oriol, A.; Moreau, P.; Yakoub-Agha, I.; Delforge, M.; Cavo, M.; Einsele, H.; Goldschmidt, H.; Weisel, K.; Rambaldi, A.; Reece, D.; Petrocca, F.; Massaro, M.; Connarn, J. N.; Kaiser, S.; Patel, P.; Huang, L.; Campbell, T. B.; Hege, K.; San-Miguel, J. (2021). "Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma". The New England Journal of Medicine. 384 (8): 705–716. doi:10.1056/NEJMoa2024850. PMID 33626253.
  5. ^ Munshi, N. C.; Anderson Jr, L. D.; Shah, N.; Madduri, D.; Berdeja, J.; Lonial, S.; Raje, N.; Lin, Y.; Siegel, D.; Oriol, A.; Moreau, P.; Yakoub-Agha, I.; Delforge, M.; Cavo, M.; Einsele, H.; Goldschmidt, H.; Weisel, K.; Rambaldi, A.; Reece, D.; Petrocca, F.; Massaro, M.; Connarn, J. N.; Kaiser, S.; Patel, P.; Huang, L.; Campbell, T. B.; Hege, K.; San-Miguel, J. (2021). "Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma". The New England Journal of Medicine. 384 (8): 705–716. doi:10.1056/NEJMoa2024850. PMID 33626253.
  6. ^ "Paving the Path to Progress in Multiple Myeloma Research". 3 January 2024.