Draft:John Kevan Healy


John Kevan Healy MBBS Hons II, FRACP edit

John Kevan Healy
 
Born1933
Sydney, Australia
EducationNorth Sydney Boys High School, Sydney University (1951 to 1956)
Occupation(s)Medical practitioner and researcher
Years active1957 - 2020

Medical Career edit

Profession - Medical practitioner

Field - Nephrologist, Renal Physician and Researcher

Work institutions:

Honorary Position

Significant Awards:

Specialisations:

Sydney University edit

A North Sydney Boys High School alumnus, John studied medicine from 1951 to 1956 at Sydney University, where he earned prizes in biochemistry and clinical medicine. He was also made a Prosector in Anatomy.[1]

 


Research Lions Renal Research Laboratory in Brisbane

Dr John K. Healy was the first  Lion's Research Fellow at the Princess Alexandra Hospital. He started the LIONS Renal Research Laboratory in Brisbane in 1966, with additional funding from the National Heart Foundation and the National Health and Medical Research Council of Australia. During his tenure at the Lion’s Renal Research Laboratory, he published internationally recognised articles on renal research and developed a widely accepted kidney function test.[2]

 
LIONS Renal Research Lab at PA John with Jon Douglas and Rosebelle Graham in 1967

Post LIONS Renal Research Laboratory edit

In 1979 John returned to clinical work, he centered his practice on the Brisbane Clinic on Wickham Terrace, Brisbane and the Wesley Hospital. He also worked as a consultant for the Renal Unit of Royal Brisbane Hospital. At the Wesley Hospital, John started using peritoneal dialysis on a number of patients with acute renal failure. He also did the first hemodialysis there on such a patient, using a machine surplus to need from the Dialysis Unit in Townsville. This experience contributed to the initiation in 1989 of the first private dialysis unit in Brisbane, in conjunction with Dr. Philip Boyle who had a patient who came with his own machine. The Dialysis Unit has expanded over the years to become a very large private chronic Dialysis Unit.

John served for some years on the Ethics Committee of the Wesley Hospital. He became Chairman of the Medical Advisory Committee of the Wesley Hospital in 1992-3, as he was an ex-officio Member of the Wesley Hospital Board. He was made an Emeritus Fellow of that Hospital in 2003[3].

Publications edit

Notable publications:

Major publications from Dr. John K. Healy and Associates from the LIONS Renal Research Laboratory from 1966-1978.

  1. Healy, J.K. The effect of intravenous angiotensin infusion on adrenal medullary function in man.  Proc. Soc. Exptl. Biol. Med. (USA) 125:679-683, 1967. https://journals.sagepub.com/doi/abs/10.3181/00379727-125-32179
  2. Healy, J.K. Clinical assessment of glomerular filtration rate by different forms of creatinine Clearance and a modified PSP excretion test. Amer. J. Med. (USA) 44:348-358, 1968. https://www.sciencedirect.com/science/article/abs/pii/000293436890106X
  3. Healy J.K. and Douglas J.B. The effect of angiotensin on renal carbonic anhydrase. Biochim.  et Biophys. Acta  151:520-522 1968. (Netherlands). https://www.sciencedirect.com/science/article/abs/pii/0005274468901198
  4. Bryan, C.W. and Healy, J.K. Acute renal failure in myeloma. Amer. J. Med. 1968 (USA) 44:128-133, 1968. https://www.sciencedirect.com/science/article/abs/pii/0002934368902441
  5. Healy, J.K., Douglas, J.B. and Arnold, J.E. The effect of angiotensin on isolated rabbit renal tubules. Clin. Sci. (London), 37: 583-592, 1969. https://pubmed.ncbi.nlm.nih.gov/4312144/
  6. Douglas, J.B. and Healy J.K. Nephrotoxic effects of Amphotericin B, including renal tubular acidosis. Amer. J. Med. (USA) 46:154-162, 1969. https://www.sciencedirect.com/science/article/abs/pii/0002934369900679
  7. Arnold, J.E. and Healy, J.K. Hyperkalemia, hypertension and systemic acidosis associated with a tubular defect in potassium excretion. Amer. J. Med. (USA) 47:461-472, 1969. https://www.sciencedirect.com/science/article/abs/pii/0002934369902307
  8. Healy, J.K.  Diseases of the Kidneys in Medicine for the Paramedical Professions (Ed. Piper, D.W.) McGraw-Hill, (Sydney), 1970.
  9. Healy, J.K. Angiotensin and the Kidney. Urol. Digest (USA), 8:13-23, 1969.
  10. Healy, J.K. Renal Function, Anaesthesia and Surgery. Journal of the Princess Alexandra  Hospital, 19-22, 1969.
  11. Healy, J.K. Diseases of the Kidneys in Medicine for Students and Nurses, Ed. D.W.Piper. McGraw-Hill, (Sydney) Second Edition.  166-182, 1980.
  12. Healy, J.K. and Elliott, A.J. The effect of a natriuretic dose of angiotensin on rabbit kidney composition. Clin. Sci. (London), 38:727-739, 1970. https://portlandpress.com/clinsci/article-abstract/38/6/727/69271/The-Effect-of-a-Natriuretic-Dose-of-Angiotensin-on
  13. Healy, J.K. and Elliott, A.J. The transient nature of angiotensin induced natriuretic in the        rabbit. Clin.  Sci. (London), 43:355-370, 1972. https://portlandpress.com/clinsci/article-abstract/43/3/355/70057/The-Transient-Nature-of-Angiotensin-Induced
  14. Healy, J.K., Drum, P.J. and Elliott, A.J. Kanamycin dosage in renal failure. Aust. NZ . J. Med. 3: 474-479, 1973. https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1445-5994.1973.tb03125.x
  15. Healy, J.K., Elliott, A.J. and Harrison, L.C. Effects of angiotensin on plasma electrolyte concentrations in rabbits and in man.  Clin. Sci. Mol. Med. (London), 46: 19-36, 1974. https://portlandpress.com/clinsci/article-abstract/46/1/19/70700/Effects-of-Angiotensin-on-Plasma-Electrolyte
  16. Healy, J.K., Fraser, P.A. and Young, J.A. Inhibition of sodium transport by angiotensin II in the main duct of the rabbit mandibular gland isolated and perfused in vitro.  Pflugers Archiv (Germany) 363, 69-73 1976. https://link.springer.com/article/10.1007/BF00587404
  17. Healy, J.K. and Bohr, D.F. Angiotensin II responses of rabbit aortic strips compared with fast and slow epinephrine responses. Proc. Soc. Exptl. Biol. Med. (USA) 155, 495-500 1977. https://journals.sagepub.com/doi/abs/10.3181/00379727-155-39837
  18. Healy, J.K. and Elliott, A.J. Multiple changes in distal stop flow electrolyte patterns and reduction of acid excretion induced in rabbits by angiotensin. Clin. Sci. Mol. Med. (London) 50, 91-102, 1976. https://portlandpress.com/clinsci/article-abstract/50/2/91/73289/Multiple-Changes-in-Distal-Stop-Flow-Electrolyte
  19. Healy, J.K., Elliott, A.J. and Oweczkin I.J.  Influence of angiotensin II, ouabain and hydrostatic pressure on inulin and electrolyte concentrations of fluid perfusing pig carotid arteries in vitro. Clin. Science, 56,445-453, 1979. https://portlandpress.com/clinsci/article-abstract/56/5/445/72381/Influence-of-Angiotensin-II-Ouabain-and

Publications prior to LIONS Renal Research Laboratory of John Healy:

  1. Healy, J.K. Ascending Paralysis Following Malathiion Intoxication.  Med. J. Aust.Jun. 6,764-767,1959. https://www.cabdirect.org/cabdirect/abstract/19592704154
  2. Healy, J.K., Jeremy, D., Edwards, K. D.G .and Whyte, H.M. Oliguric Renal Failure: A Review of 275 Cases.  Med. J. Aust., Mar. 16, 381-386, 1963. https://onlinelibrary.wiley.com/doi/abs/10.5694/j.1326-5377.1963.tb23108.x
  3. Healy, J.K. Acute Oliguric Renal Failure Associated with Multiple Myeloma.  Brit. Med. J.,1126-1137,1963. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2123001/
  4. Healy, J.K., Edwards, K.D.G. and Whyte, H.M. Simple tests of Renal Function Using Creatinine,Phenolsulphonphthalein, and Pitressin. J. Clin. Path., 17: 557-563,1963. https://jcp.bmj.com/content/17/5/557.short
  5. Healy, J.K.,Barcena, C., O’Connell, J.M.B.,and Schreiner, G.E.  Renal and Pressor Action of Angiotensin In the Normal Dog. Amer. J. Physiol., 208:1093-1099,1965. https://jcp.bmj.com/content/17/5/557.short
  6. Healy, J.K., Barcena and Schreiner, G.E. Effect of Angiotensin on Maximal Tubular Transport of PAH and Glucose in Dogs. Amer. J. Physiol., 209. 651-654, 1965. https://journals.physiology.org/doi/abs/10.1152/ajplegacy.1965.209.3.651
  7. Healy,J.K., Suszkiw, J.B. and Schreiner, G.E. Effect of Angiotensin II on Blood Glucose Level in the dog.Proc. Soc. Exptl. Med., 119: 734-736, 1965. https://journals.sagepub.com/doi/abs/10.3181/00379727-119-30285?journalCode=ebma
  8. Healy, J.K.,Suszkiw, J.B.,Dennis, V.W. and Schreiner, G.E. Effect of Aldosterone and Salt Intake on Renal and Pressor Actions of Angiotensin. Nephron: 3: 329-343, 1966. https://karger.com/nef/article-abstract/3/6/329/213139/Effect-of-Aldostetone-and-Salt-Intake-on-Renal-and?redirectedFrom=fulltext
  9. Healy, J.K. The Effect of IV Angiotensin Infusion on Adrenal Medullary Function in Man. Proc. Soc. Exptl. Biol.Med. 125: 679-683,1967. https://journals.sagepub.com/doi/abs/10.3181/00379727-125-32179?journalCode=ebma
  10. Healy, J.K. Clinical Assessment of GFR by Different Forms of Creatinine Clearance and a Modified PSP Excretion Test. Amer. J. Med.44:348-358, 1968. https://www.sciencedirect.com/science/article/abs/pii/000293436890106X
  11. Healy, J.K. and Douglas J.B. The Effect of  Angiotensin on Renal Carbonic Anhydrase. Biochim. Biophys. Acta, 151:520-522.
  12. Bryan, C.W. and Healy, J.K.  Acute Renal Failure in Myeloma. Amer. J. Med. 44:128-133, 1968. https://www.sciencedirect.com/science/article/abs/pii/0002934368902441
  13. Healy, J.K., Douglas, J.B. and Arnold, J.E. The Effect of Angiotensin on Isolated Rabbit Renal Tubules Clin. Sci. (London), 37: 583-592. 1969. https://pubmed.ncbi.nlm.nih.gov/4312144/
  14. Douglas, J.B. and Healy, J.K. Nephrotoxic Effects of Amphotericin B, Including Renal Tubular Acidosis. Amer. J. Med.46:154-162. https://pubmed.ncbi.nlm.nih.gov/4951424/
  15. Arnold, J.E. and Healy J.K.  Hyperkalemia, Hypertension and Systemic  Acidosis Without Renal Failure Associated with a Tubular Defect in Potassium excretion.  Amer. J. Med. 47: 461-472. https://pubmed.ncbi.nlm.nih.gov/5808659/
  16. Healy, J.K. Diseases of the Kidneys  in Medicine for the Paramedical Professions (Ed. Piper, D.W.) McGraw Hill (Sydney), 1970.
  17. Healy, J.K. Angiotensin and the Kidney. Urology Digest.  8:13-23.
  18. Healy, J.K. Renal  Function, Anesthesia and Surgery.  J. Princ.. Alexandra Hospital, 19-22, 1969.
  19. Healy, J.K. Diseases of the Kidneys  in Medicine for Students and Nurses. Ed. (D.W. Piper), McGraw Hill (Sydney), 2nd Ed. 166-182, 1980.
  20. Healy, J.K. and Elliott, A.J. The Effect of a Natriuretic Dose of Angiotensin on Rabbit Kidney Composition. Clin.  Sci. (London), 38: 727-739.  1970.
  21. Healy, J. K. and Elliott, A.J. The Transient Nature of Angiotensin-induced Natriuresis  in the Rabbit. Clin. Sci. (London), 43:355-370. 1972.
  22. Healy, J.K., Drum, P.J. and Elliott, A.J. Kanamycin Dosage in Renal Failure.  Aust. and NZ J. Med. 3; 474-479, 1973. https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1445-5994.1973.tb03125.x
  23. Healy, J.K. , Elliott A.J., and Harrison, L.C. Effects of Angiotensin on Plasma Electrolyte Conc-entrations in Rabbits and in Man. Clin. Sci. Molecular Med. (London), 46:19-36. 1974. https://portlandpress.com/clinsci/article-abstract/46/1/19/70700/Effects-of-Angiotensin-on-Plasma-Electrolyte
  24. Healy, J.K., Fraser, P.A. and Young, J.A. Inhibition of Sodium Transport by Angiotensin II in the Main Duct of the Rabbit Mandibular Gland Isolated and Perfused in vitro. Pflugers Archiv (Germany) 363: 69-73, 1976. https://link.springer.com/article/10.1007/BF00587404
  25. Healy, J.K. and Bohr, D.F. Angiotensin II Responses of Rabbit Aortic Strips Compared with Fast And Slow Epinephrine Responses. Proc. Soc. Exptl. Biol. Med. 155:495-500, 1976. https://journals.sagepub.com/doi/abs/10.3181/00379727-155-39837?journalCode=ebma
  26. Healy, J.K. and Elliott, A.J. Multiple Changes in Distal Stop-flow Electrolyte Patterns and Reduction of Acid Excretion Induced in Rabbits by Angiotensin. Clin. Sci. Mol. Med.(London)  50: 91-102,1976.   https://portlandpress.com/clinsci/article-abstract/50/2/91/73289/Multiple-Changes-in-Distal-Stop-Flow-Electrolyte
  27. Healy. J.K., Elliott, A.J. and Oweczkin, I.J. Influence of Angiotensin II, Ouabain and Hydrostatic Pressure on Inulin and Electrolyte Concentrations of Fluid Perfusing Pig Carotid Arteries in vitro.  Clin. Sci. Mol Med. (London)  56:445-453, 1979.
  28. Healy, J.K., Searle, J.W. and Monnington, P.K. Exacerbations of IgA Nephropathy with Recurrent Acute Mastitis. Amer. J. Kidney, Dis.,16:166-167, 1990.
  29. Healy, J.K. Pseudohypoaldosteronism Type II; History, Arguments Answers and Still Some Questions. Hypertension, 63:648-654, 2014.  https://www.ahajournals.org/doi/full/10.1161/HYPERTENSIONAHA.113.02187
  30. Healy, J.K. Hyperkalemia in Pseudo hypoaldosteronism Type 2 can be from Mutated WNK4, but more often from Impaired Ubiquitination of Normal WNK4. Kidney International.  In the press, 2020. https://www.kidney-international.org/article/S0085-2538(20)30561-5/fulltext

References edit

  1. ^ "- Our people - Sydney Medical School - The University of Sydney". www.sydney.edu.au. Retrieved 2024-05-14.
  2. ^ "History". Lions Medical Research Foundation. Retrieved 2024-04-21.
  3. ^ "Medical advisory committee". www.wesley.com.au. Retrieved 2024-04-21.