Dieticyclidine (PCDE), or diethylphenylcyclohexylamine, is a psychoactive drug and research chemical of the arylcyclohexylamine chemical class related to phencyclidine (PCP) and eticyclidine (PCE). It acts as an NMDA receptor antagonist but has low potency and acts mainly as a prodrug for eticyclidine.[1][2]

Dieticyclidine
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
  • N,N-diethyl-1-phenylcyclohexan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H25N
Molar mass231.383 g·mol−1
3D model (JSmol)
  • CCN(CC)C1(CCCCC1)C2=CC=CC=C2
  • InChI=1S/C16H25N/c1-3-17(4-2)16(13-9-6-10-14-16)15-11-7-5-8-12-15/h5,7-8,11-12H,3-4,6,9-10,13-14H2,1-2H3 ☒N
  • Key:GRHWLIMQOFAGHA-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

References

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  1. ^ Cho AK, Hiramatsu M, Schmitz DA, Landaw EM, Chang AS, Ramamurthy S, Jenden DJ (1993). "A pharmacokinetic study of phenylcyclohexyldiethylamine. An analog of phencyclidine". Drug Metabolism and Disposition. 21 (1): 125–32. PMID 8095205.
  2. ^ Cho AK, Hiramatsu M, Schmitz DA, Vargas HM, Landaw EM (March 1993). "A behavioral and pharmacokinetic study of the actions of phenylcyclohexyldiethylamine and its active metabolite, phenylcyclohexylethylamine". The Journal of Pharmacology and Experimental Therapeutics. 264 (3): 1401–5. PMID 8450474.