Dibutylchloromethyltin chloride (DBCT) is a toxic organotin compound. It's a potent and irreversible ATP synthase inhibitor.[1][2][3] DBCT is a volatile liquid with powerful vesicant effects.[1]
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| Names | |
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| IUPAC name
Dibutyl(chloro)(chloromethyl)stannane
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| Other names
DBCT
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| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C9H20Cl2Sn | |
| Molar mass | 317.87 g·mol−1 |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards
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Toxic, vesicant |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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See also
editReferences
edit- ^ a b Cain, K; Partis, MD; Griffiths, DE (15 September 1977). "Dibutylchloromethyltin chloride, a covalent inhibitor of the adenosine triphosphate synthase complex". The Biochemical Journal. 166 (3): 593–602. doi:10.1042/bj1660593. PMC 1165045. PMID 145860.
- ^ Moore, Anthony L.; Linnett, Paul E.; Beechey, R. Brian (August 1980). "Dibutylchloromethyltin chloride, a potent inhibitor of electron transport in plant mitochondria". Journal of Bioenergetics and Biomembranes. 12 (3–4): 309–323. doi:10.1007/bf00744691. PMID 7217044. S2CID 29130410.
- ^ Diwan, Joyce Johnson (February 1982). "Some effects of dibutylchloromethyltin chloride and other reagents on mitochondrial K+ flux". Journal of Bioenergetics and Biomembranes. 14 (1): 15–22. doi:10.1007/bf00744076. PMID 7142136. S2CID 24153839.
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