De Boer is a Dutch occupational surname meaning "the farmer". Variant spellings include den Boer and DeBoer. Notable people with this surname include:

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  • Kalen DeBoer (born 1974), American football coach and player
  • Kito de Boer (born 1957), Dutch businessman and art collector
  • Klaas de Boer (born 1942), Dutch-born U.S. soccer player and coach

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