Darren Lewis (born 1967) is an American baseball player.
Darren Lewis may also refer to:
- Darren Lewis (American football) (1968–2024), American professional football player
- Darren Lewis, American songwriter, co-writer of "Smile (Lily Allen song)" and "Ay Yo"
See also
edit- Darin Lewis (born 1976), Trinidadian soccer player