Darrell Lester may refer to two professional American football players:
- Darrell Lester (center) (1914–1993), center for the Green Bay Packers (1937–1938)
- Darrell Lester (fullback) (1940–2006), fullback for the Minnesota Vikings (1964) and Denver Broncos (1965–1966)
This disambiguation page lists articles about people with the same name.
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