Dark Zone may refer to:
- Dark Zone, a universe in the Lexx television series
- Dark Zone, a concept in the Futari wa Pretty Cure anime series
- The Dark Zone, the Quake map (DM6) setting of the 1996 film Diary of a Camper
- Dark Zones, concepts in the video game Tom Clancy's The Division
- "Dark Zone", an episode of the History Channel show Shadow Force
- Dark Zone, a 2011 novel by Yusuke Kishi
- In immunology, the proliferative compartment of the germinal center reaction
This disambiguation page lists articles associated with the title Dark Zone.
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