D-lactate dehydratase (EC 4.2.1.130, glyoxylase III) is an enzyme with systematic name (R)-lactate hydro-lyase.[1][2] This enzyme catalyses the following chemical reaction

D-lactate dehydratase
Identifiers
EC no.4.2.1.130
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
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PDB structuresRCSB PDB PDBe PDBsum
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(R)-lactate methylglyoxal + H2O

The enzyme converts methylglyoxal to (R)-lactate.

References

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  1. ^ Misra K, Banerjee AB, Ray S, Ray M (February 1995). "Glyoxalase III from Escherichia coli: a single novel enzyme for the conversion of methylglyoxal into D-lactate without reduced glutathione". The Biochemical Journal. 305 (3): 999–1003. doi:10.1042/bj3050999. PMC 1136357. PMID 7848303.
  2. ^ Subedi KP, Choi D, Kim I, Min B, Park C (August 2011). "Hsp31 of Escherichia coli K-12 is glyoxalase III". Molecular Microbiology. 81 (4): 926–36. doi:10.1111/j.1365-2958.2011.07736.x. PMID 21696459.
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