Constitutive ablation refers to gene expression which results in cell death.[1] Constitutive cell ablation can be induced by diphtheria toxin (DT) in zebrafish.[2]

See also

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References

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  1. ^ Ohnmacht, Caspar; Pullner, Andrea; King, Susan B. S.; Drexler, Ingo; Meier, Stefanie; Brocker, Thomas; Voehringer, David (2009). "Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity". Journal of Experimental Medicine. 206 (3): 549–59. doi:10.1084/jem.20082394. PMC 2699126. PMID 19237601.
  2. ^ Kristen, Sadler (21 March 2017). Zebrafish at the Interface of Development and Disease Research. Academic Press. p. 259. ISBN 9780128033432.
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