In enzymology, a cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase (EC 1.3.1.29) is an enzyme that catalyzes the chemical reaction
| cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.3.1.29 | ||||||||
| CAS no. | 53986-49-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- cis-1,2-dihydronaphthalene-1,2-diol + NAD+ naphthalene-1,2-diol + NADH + H+
Thus, the two substrates of this enzyme are cis-1,2-dihydronaphthalene-1,2-diol and NAD+, whereas its 3 products are naphthalene-1,2-diol, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase. Other names in common use include (+)-cis-naphthalene dihydrodiol dehydrogenase, naphthalene dihydrodiol dehydrogenase, and cis-dihydrodiol naphthalene dehydrogenase. This enzyme participates in 1- and 2-methylnaphthalene degradation and naphthalene and anthracene degradation.
References
edit- Patel TR, Gibson DT (1974). "Purification and properties of (plus)-cis-naphthalene dihydrodiol dehydrogenase of Pseudomonas putida". J. Bacteriol. 119 (3): 879–88. PMC 245694. PMID 4369091.
