Christophe Dessimoz is a Swiss National Science Foundation (SNSF) Professor at the University of Lausanne, Associate Professor at University College London and a group leader at the Swiss Institute of Bioinformatics.[5][2][6][7][8] He was awarded the Overton Prize in 2019 for his contributions to computational biology.[1] Starting in April 2022, he will be joint executive director of the SIB Swiss Institute of Bioinformatics, along with Ron Appel.
Christophe Dessimoz | |
|---|---|
.jpg) Christophe Dessimoz speaking at the Intelligent Systems for Molecular Biology (ISMB) / European Conference on Computational Biology (ECCB) in Basel, 2019 | |
| Born | Christophe Dessimoz 1980 (age 43–44) |
| Alma mater | ETH Zurich (MSc, PhD) |
| Known for | Orthologous MAtrix (OMA)[4] |
| Awards | Overton Prize (2019)[1] |
| Scientific career | |
| Fields | Bioinformatics Genomics Phylogenetics Evolution Computational Biology[2] |
| Institutions | University of Lausanne European Bioinformatics Institute University College London Swiss Institute of Bioinformatics |
| Thesis | Comparative Genomics Using Pairwise Evolutionary Distances (2009) |
| Doctoral advisor | Gaston Gonnet[3] |
| Website | lab |
Education
editDessimoz obtained his Master of Science degree in 2003[5] and PhD in Computer Science in 2009 from ETH Zurich in Switzerland[9] where his doctoral research was supervised by Gaston Gonnet[3] and examined by Amos Bairoch.[9]
Career and research
editAfter postdoctoral research at the European Bioinformatics Institute (EBI) on the Wellcome Genome Campus in Hinxton, Cambridgeshire,[10] he joined University College London (UCL) as lecturer in 2013, and was promoted to Reader in 2015.[5] In 2015, he joined the University of Lausanne as professor, retaining an appointment at UCL.[11] Since 2016, Dessimoz has served as group leader at the Swiss Institute of Bioinformatics[5] where his research interests are in bioinformatics, genomics, phylogenetics, evolution and computational biology.[2][12][13][14][15]
Dessimoz is known for his management of the Orthologous MAtrix (OMA)[4] which provides information on orthologous proteins. OMA has important applications in protein function prediction.[1] Dessimoz's approach to benchmarking had a major impact on three key subfields of computational biology: orthology inference, sequence alignment, and the gene ontology (GO).[1][16][17]
Awards and honours
editDessimoz was awarded the Overton Prize by the International Society for Computational Biology (ISCB) in 2019 for outstanding contributions to computational biology.[1]
References
edit- ^ a b c d e Kovats, Diane; Shamir, Ron; Fogg, Christiana (2019). "2019 ISCB Overton Prize: Christophe Dessimoz". F1000Research. 8: 722. doi:10.12688/f1000research.19220.1. ISSN 2046-1402. PMC 6534074. PMID 31164977.
- ^ a b c Christophe Dessimoz publications indexed by Google Scholar
- ^ a b Christophe Dessimoz at the Mathematics Genealogy Project
- ^ a b Altenhoff, Adrian M; Glover, Natasha M; Train, Clément-Marie; Kaleb, Klara; Warwick Vesztrocy, Alex; Dylus, David; de Farias, Tarcisio M; Zile, Karina; Stevenson, Charles; Long, Jiao; Redestig, Henning; Gonnet, Gaston H; Dessimoz, Christophe (2018). "The OMA orthology database in 2018: retrieving evolutionary relationships among all domains of life through richer web and programmatic interfaces". Nucleic Acids Research. 46 (D1): D477–D485. doi:10.1093/nar/gkx1019. ISSN 0305-1048. PMC 5753216. PMID 29106550.
- ^ a b c d Dessimoz, Christophe (2019). "Dessimoz Lab". lab.dessimoz.org.
- ^ Christophe Dessimoz publications from Europe PubMed Central
- ^ Christophe Dessimoz publications indexed by the Scopus bibliographic database. (subscription required)
- ^ Christophe Dessimoz on Twitter
- ^ a b Dessimoz, Christophe (2009). Comparative Genomics Using Pairwise Evolutionary Distances. ethz.ch (PhD thesis). ETH Zurich. doi:10.3929/ethz-a-005762050. hdl:20.500.11850/72801. OCLC 935351416.
- ^ Goldman, Nick; Bertone, Paul; Chen, Siyuan; Dessimoz, Christophe; LeProust, Emily M.; Sipos, Botond; Birney, Ewan (2013). "Towards practical, high-capacity, low-maintenance information storage in synthesized DNA". Nature. 494 (7435): 77–80. Bibcode:2013Natur.494...77G. doi:10.1038/nature11875. ISSN 0028-0836. PMC 3672958. PMID 23354052.
- ^ "Dr Christophe Dessimoz". ucl.ac.uk. Retrieved 6 March 2019.
- ^ Wodak, Shoshana; Sunnåker, Mikael; Busetto, Alberto Giovanni; Numminen, Elina; Corander, Jukka; Foll, Matthieu; Dessimoz, Christophe (2013). "Approximate Bayesian Computation". PLOS Computational Biology. 9 (1): e1002803. Bibcode:2013PLSCB...9E2803S. doi:10.1371/journal.pcbi.1002803. ISSN 1553-7358. PMC 3547661. PMID 23341757.
- ^ Anisimova, Maria; Gil, Manuel; Dufayard, Jean-François; Dessimoz, Christophe; Gascuel, Olivier (2011). "Survey of Branch Support Methods Demonstrates Accuracy, Power, and Robustness of Fast Likelihood-based Approximation Schemes". Systematic Biology. 60 (5): 685–699. doi:10.1093/sysbio/syr041. ISSN 1076-836X. PMC 3158332. PMID 21540409.
- ^ Eisen, Jonathan A.; Altenhoff, Adrian M.; Dessimoz, Christophe (2009). "Phylogenetic and Functional Assessment of Orthologs Inference Projects and Methods". PLOS Computational Biology. 5 (1): e1000262. Bibcode:2009PLSCB...5E0262A. doi:10.1371/journal.pcbi.1000262. ISSN 1553-7358. PMC 2612752. PMID 19148271.
- ^ Abbosh, Christopher; Birkbak, Nicolai J.; Wilson, Gareth A.; Jamal-Hanjani, Mariam; Constantin, Tudor; Salari, Raheleh; Le Quesne, John; Moore, David A.; Veeriah, Selvaraju; Rosenthal, Rachel; Marafioti, Teresa; et al. (2017). "Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution". Nature. 545 (7655): 446–451. Bibcode:2017Natur.545..446A. doi:10.1038/nature22364. ISSN 0028-0836. PMC 5812436. PMID 28445469.
- ^ Dessimoz, Christophe (2017). Dessimoz, Christophe; Škunca, Nives (eds.). The Gene Ontology Handbook. Methods in Molecular Biology. Vol. 1446. doi:10.1007/978-1-4939-3743-1. ISBN 9781493937431. ISSN 1064-3745. S2CID 3708801.
- ^ Gaudet, Pascale; Škunca, Nives; Hu, James C.; Dessimoz, Christophe (2017). "Primer on the Gene Ontology". The Gene Ontology Handbook. Methods in Molecular Biology. Vol. 1446. pp. 25–37. doi:10.1007/978-1-4939-3743-1_3. ISBN 978-1-4939-3741-7. ISSN 1064-3745. PMC 6377150. PMID 27812933.
