Christian Kurts (born 27 November 1964 in Helmstedt, Germany) is a German immunologist and nephrologist.

Career edit

Since 2009, Christian Kurts has been the Director Institute of Experimental Immunology,[1] University Hospital Bonn, University of Bonn, Germany. In 2016, he founded the Bonn & Melbourne Research and Graduate training group (Bo&MeRanG) and remains a Co-Spokesperson of the Deutsche Forschungsgemeinschaft-funded program.[2]

Scientific interests edit

Christian Kurts in known for publications in the fields of cross-presentation,[3][4][5] and immune tolerance as well as his work on the function of dendritic cells in a variety of organs, with a particular focus on the urogenital tract.[6][7][4][8][9]

Awards edit

In 2012, he shared the Gottfried Wilhelm Leibniz Prize with Gunther Hartmann for their "seminal discoveries concerning the mode of action of the body’s endogenous defence systems."[10]

References edit

  1. ^ "Prof. Dr. med. Christian Kurts" (PDF).
  2. ^ "Bo&MeRanG Bonn & Melbourne / GRK 2168". Archived from the original on 2020-07-29. Retrieved 2019-02-20.
  3. ^ Burgdorf, Sven; Kautz, Andreas; Böhnert, Volker; Knolle, Percy A.; Kurts, Christian (27 April 2007). "Distinct Pathways of Antigen Uptake and Intracellular Routing in CD4 and CD8 T Cell Activation". Science. 316 (5824). American Association for the Advancement of Science (AAAS): 612–616. Bibcode:2007Sci...316..612B. doi:10.1126/science.1137971. ISSN 0036-8075. PMID 17463291. S2CID 40811442.
  4. ^ a b Kurts, Christian; Robinson, Bruce W. S.; Knolle, Percy A. (2010). "Cross-priming in health and disease". Nature Reviews Immunology. 10 (6). Springer Science and Business Media LLC: 403–414. doi:10.1038/nri2780. ISSN 1474-1733. PMID 20498667. S2CID 25318142.
  5. ^ Semmling, Verena; Lukacs-Kornek, Veronika; Thaiss, Christoph A; Quast, Thomas; Hochheiser, Katharina; Panzer, Ulf; Rossjohn, Jamie; Perlmutter, Patrick; Cao, Jia; Godfrey, Dale I; Savage, Paul B; Knolle, Percy A; Kolanus, Waldemar; Förster, Irmgard; Kurts, Christian (28 February 2010). "Alternative cross-priming through CCL17-CCR4-mediated attraction of CTLs toward NKT cell–licensed DCs". Nature Immunology. 11 (4). Springer Science and Business Media LLC: 313–320. doi:10.1038/ni.1848. ISSN 1529-2908. PMID 20190758. S2CID 31211161.
  6. ^ Heymann, Felix; Meyer-Schwesinger, Catherine; Hamilton-Williams, Emma E.; Hammerich, Linda; Panzer, Ulf; Kaden, Sylvia; Quaggin, Susan E.; Floege, Jürgen; Gröne, Hermann-Josef; Kurts, Christian (1 May 2009). "Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injury". Journal of Clinical Investigation. 119 (5). American Society for Clinical Investigation: 1286–1297. doi:10.1172/jci38399. ISSN 0021-9738. PMC 2673875. PMID 19381017.
  7. ^ Engel, Daniel R; Koscielny, Arne; Wehner, Sven; Maurer, Juliane; Schiwon, Marzena; Franken, Lars; Schumak, Beatrix; Limmer, Andreas; Sparwasser, Tim; Hirner, Andreas; Knolle, Percy A; Kalff, Jörg C; Kurts, Christian (28 November 2010). "T helper type 1 memory cells disseminate postoperative ileus over the entire intestinal tract". Nature Medicine. 16 (12). Springer Science and Business Media LLC: 1407–1413. doi:10.1038/nm.2255. ISSN 1078-8956. PMID 21113155. S2CID 23226382.
  8. ^ Kurts, Christian; Panzer, Ulf; Anders, Hans-Joachim; Rees, Andrew J. (16 September 2013). "The immune system and kidney disease: basic concepts and clinical implications". Nature Reviews Immunology. 13 (10). Springer Science and Business Media LLC: 738–753. doi:10.1038/nri3523. ISSN 1474-1733. PMID 24037418. S2CID 205492119.
  9. ^ Schiwon, Marzena; Weisheit, Christina; Franken, Lars; Gutweiler, Sebastian; Dixit, Akanksha; Meyer-Schwesinger, Catherine; Pohl, Judith-Mira; Maurice, Nicholas J.; Thiebes, Stephanie; Lorenz, Kristina; Quast, Thomas; Fuhrmann, Martin; Baumgarten, Georg; Lohse, Martin J.; Opdenakker, Ghislain; Bernhagen, Jürgen; Bucala, Rick; Panzer, Ulf; Kolanus, Waldemar; Gröne, Hermann-Josef; Garbi, Natalio; Kastenmüller, Wolfgang; Knolle, Percy A.; Kurts, Christian; Engel, Daniel R. (2014). "Crosstalk between Sentinel and Helper Macrophages Permits Neutrophil Migration into Infected Uroepithelium". Cell. 156 (3). Elsevier BV: 456–468. doi:10.1016/j.cell.2014.01.006. ISSN 0092-8674. PMC 4258064. PMID 24485454.
  10. ^ "DFG, German Research Foundation – Prof. Dr. Gunther Hartmann & Prof. Dr. Christian Kurts". www.dfg.de.