Chlodantane

Chlodantane
Clinical data
Other names	ADK-910; Chlodantan; N-(2-Adamantyl)-N-(para-chlorobenzoyl)amine; 2-(para-Chlorobenzoylamino)adamantane
Identifiers
	IUPAC name N-(2-adamantyl)-4-chlorobenzamide;
PubChem CID	959689;
ChemSpider	832832;
Chemical and physical data
Formula	C17H20ClNO
Molar mass	289.80 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1C2CC3CC1CC(C2)C3NC(=O)C4=CC=C(C=C4)Cl;
	InChI InChI=1S/C17H20ClNO/c18-15-3-1-12(2-4-15)17(20)19-16-13-6-10-5-11(8-13)9-14(16)7-10/h1-4,10-11,13-14,16H,5-9H2,(H,19,20); Key:VOHIYJJUKAUCCU-UHFFFAOYSA-N;

Chlodantane (developmental code name ADK-910) is a drug described as an adaptogen or actoprotector "of the estrogen activity type" that was developed in Russia and was never marketed.^[1]^[2] It is an adamantane derivative and is closely related to bromantane (N-(2-adamantyl)-N-(para-bromophenyl)amine) and other adamantanes.^[2]^[1] It has been said to improve physical performance.^[2] However, only animal or cell culture research has been conducted and it has not been studied in humans.^[2] The drug is described as having a broader spectrum of activity than bromantane.^[1] It also has immunostimulant effects that are said to be more pronounced than those of bromantane.^[1]

References

^ ^a ^b ^c ^d Morozov IS, Ivanova IA, Lukicheva TA (2001). "Actoprotector and Adaptogen Properties of Adamantane Derivatives (A Review)". Pharmaceutical Chemistry Journal. 35 (5): 235–238. doi:10.1023/A:1011905302667.
^ ^a ^b ^c ^d Oliynyk S, Oh S (September 2012). "The pharmacology of actoprotectors: practical application for improvement of mental and physical performance". Biomolecules & Therapeutics. 20 (5): 446–456. doi:10.4062/biomolther.2012.20.5.446. PMC 3762282. PMID 24009833.

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[MorozovIvanovaLukicheva2001-1] Morozov IS, Ivanova IA, Lukicheva TA (2001). "Actoprotector and Adaptogen Properties of Adamantane Derivatives (A Review)". Pharmaceutical Chemistry Journal. 35 (5): 235–238. doi:10.1023/A:1011905302667.

[OliynykOh2012-2] Oliynyk S, Oh S (September 2012). "The pharmacology of actoprotectors: practical application for improvement of mental and physical performance". Biomolecules & Therapeutics. 20 (5): 446–456. doi:10.4062/biomolther.2012.20.5.446. PMC 3762282. PMID 24009833.

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